Hormone of Middle Lobe of Pituitary Melanocyte Stimulating Hormones
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چکیده
The hormones secreted by intermediate lobe or middle lobe of pituitary gland are called melanocyte stimulating hormones or MSH. POMC is the precursor molecule which is cleaved by proteases to give ACTH and β-lipotropin. The ACHT is further cleaved to β-MSH which has 13 amino acids. There is also α-MSH which is present in larger quantities. Amino acids 11-17 of β-MSH are common to both α-MSH and ACTH. MSH darkens the skin and is involved in skin pigmentation by deposition of melanin by melanocytes.
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